Giulia Montagna

Enthusiastic molecular biologist interested in discovering the molecular mechanisms developing and maintaining one of the hardest biological tissues: bone. Giulia leverages pathogenic conditions in which one gene/protein is affected to understand the function of that gene/protein. So far, she has focused on Osteogenesis Imperfecta, Progressive Pseudorheumatoid Arthropathy of Childhood, Camptodactyly-Arthropathy-Coxa vara-Pericarditis syndrome, and achondrogenesis type 1a. She applies genetics and molecular biology approaches to generate transgenic animal models of the disease in question to dissect the disease pathogenesis at the cellular level. On the side, she also tries to optimize open-source spatial transcriptomics techniques, like Light-Seq (Kishi et al., 2022).

While waiting for incubations and centrifuges, Giulia can be found stealing snacks from the Harris lab Situation Room.

PublicationsPermalink

• Montagna G., Pani G., Flinkman D., Cristofaro F., Pascucci B., Massimino L., Lamparelli L. A., Fassina L., James P., Coffey E., Rea G., Visai L., Rizzo A. M.* (2022). Long-term osteogenic differentiation of human bone marrow stromal cells in simulated microgravity: novel proteins sighted Cellular and Molecular Life Sciences

• Bloise N., Waldorff E.I., Montagna G., Bruni G., Fassina L., Fang S., Zhang N., Jiang J., Ryaby J.T., Visai L. (2022). Early osteogenic markers expression in hMSCs cultured onto acid etching-derived micro- and nanotopography 3D printed titanium surfaces International Journal of Molecular Sciences

• G. Montagna, F. Cristofaro, L. Fassina, G. Bruni, L. Cucca, A. Kochen, P. Pajevic Divieti, B. Bragdon, L. Visai, L. Gerstenfeld. (2020). An in vivo Comparison Study Between Strontium Nanoparticles and rhBMP2 Frontiers in Bioengineering and Biotechnology – Nanobiotechnology.

AbstractsPermalink

• Woronowicz, K.C., Montagna, G., Bailon-Zambrano, R., Warman, M.L., Nichols, J.T., Harris, M.P., (2024)., Kansas City, MO. Setting aside differences: undescribed skeletal-like progenitors as fodder for development and evolution. Society for Craniofacial Genetics and Developmental Biology

• Giulia Montagna, Steven Hann, Yiping Zhou, Mantu Bhaumik, Christina M. Jacobsen, Matthew L. Warman. (2024) A Conditional Genetic Mouse Model of Osteogenesis Imperfecta. Gordon Conference for Bone and Teeth